The Professional Footballers' Association's Chief Executive Officer Maheta Molango has stated that players may be forced to take legal action due to the crammed schedule.
The UEFA Champions League group stage will increase to 36 teams from 32, playing in a single-league format, from the 2024-25 season. Each team will play a minimum of eight matches under the new format.
Quiet a few Premier League managers have expressed their concerns over the busy schedule and its impact on players.
"I feel like we've reached a stage where people are ready to take legal action, where people are ready to take tangible action on the pitch to try to resolve it, because it's a sad state of affairs," Molango told Sky News.
"I think it's a defeat for football when the players need to take the justice in their own hands because they don't feel protected."
FIFA's revamped Club World Cup, which is set to feature 32 teams and is scheduled for 2025, will be held from June 15 to July 13, while a new Intercontinental Cup will take place annually from 2024.
The dates of the Club World Cup will only give a brief time to rest, to the European teams who qualify, between the 2024-25 and 2025-26 seasons.
When questioned if competition organisers risk killing football, Molango said: "I think that the players are ready now to take a strong stance.
"I do think that the authorities who are supposed to protect the players and protect the games are not doing that. They are generating more competitions, generating more income to the detriment of the players."
He added that the current calendar makes it "physically, humanly impossible" for the players to perform at their best level.